Mechanisms of
Sperm Motility:
Dr. Charles Lindemann
Dr. Lindemann's Publications
Note: Clicking the author's link will take you to the abstract on pubmed.gov. All links open in a new window.
  Lesich, K.A., C.B. Kelsch, K.L. Ponichter, B.J. Dionne, L. Dang and C.B. Lindemann. (2012) The calcium response of mouse sperm flagella: Role of calcium ions in the regulation of dynein activity. Biology of Reproduction in press.
  Lindemann C.B. (2011) Experimental evidence for the geometric clutch hypothesis. Current Topics in Developmental Biology 95: 1-31.
  Lesich, K.A., Z. Zhang, C. Kelsch, K. Ponichter, J.F. Strauss III and C.B. Lindemann (2010) Functional Deficiencies and a Reduced Response to Calcium in the Flagellum of Mouse Sperm Lacking SPAG16L.  Biology of Reproduction 82: 736-744.
  C.B. Lindemann and K.A. Lesich (2010) Flagellar and ciliary beating: The proven and the possible. Journal of Cell Science 123:519-528.
  Lindemann C.B. (2009)  Heart of the beat (the flagellar beat, that is) Biophysical Journal 97: 2865-6.
  Lindemann C.B. and Lesich K.A. (2009) Detergent-extracted models for the study of cilia or flagella. Methods in Molecular Biology 586:337-53.
  Pelle D.W., C.J. Brokaw, K.A. Lesich and C.B. Lindemann (2009) Mechanical properties of the passive sea urchin flagellum. Cell Motility and the Cytoskeleton 66:721-735.
  Lorch D.P., C.B. Lindemann and A.J. Hunt (2008) The motor activity of mammalian axonemal dynein studied in situ on doublet microtubules Cell Motility and the Cytoskeleton 65:487-494.
  Lesich, K.A., D.W. Pelle and C.B. Lindemann. (2008) Insights into the mechanism of ADP action on flagellar motility derived from studies on bull sperm. Biophysical Journal 95:472-482.
  Lindemann C.B. and Mitchell D. R. (2007) Evidence for Axonemal Distortion During the Flagellar Beat of Chlamydomonas. Cell Motility and the Cytoskeleton 64:580-589.
  Lindemann C.B. (2007) The Geometric Clutch as a working hypothesis for future research on cilia and flagella. Annals of the New York Academy of Sciences 1101:477-493.
  Lindemann C.B., L.J. Macauley and K.A. Lesich (2005) The counterbend phenomenon in dynein-disabled rat sperm flagella and what it reveals about the interdoublet elasticity. Biophysical Journal 89:1165-74.
  Lindemann C.B. (2004) Testing the geometric clutch hypothesis. Biology of the Cell 96:681-90.
  Schmitz-Lesich K.A. and C.B. Lindemann (2004) Direct measurement of the passive stiffness of rat sperm and implications to the mechanism of the calcium response. Cell Motility and the Cytoskeleton 59:169-79.
  Lindemann, C.B. and A. J. Hunt (2003) Does axonemal dynein push, pull, or oscillate? Cell Motility and the Cytoskeleton 56:237-44.
  C.B. Lindemann (2002) Geometric Clutch model version 3: The role of the inner and outer arm dyneins in the ciliary beat. Cell Motility and the Cytoskeleton 52:242-254.
  Moritz, M.J., K.A. Schmitz and C.B. Lindemann (2001) Measurement of the force and torque produced in the calcium response of reactivated rat sperm flagella. Cell Motility and the Cytoskeleton 49:33-40.
  Lindemann, C.B. and K.A Schmitz (2001) Detergent-extracted models for the study of cilia or flagella in Cytoskeleton Methods and Protocols Edited by R.H. Gavin Humana Press, New Jersey. Methods in Molecular Biology 161:241-252.
  Schmitz, K.A., D.L. Holcomb-Wygle, D.O. Oberski, and C.B. Lindemann (2000) Measurement of the force produced by an intact bull sperm flagellum in isometric arrest and estimation of the dynein stall force. Biophysical Journal 79:468-478.
  Holcomb-Wygle, D.L., K.A. Schmitz, and C.B. Lindemann (1999) The flagellar beat of bull sperm arrests when t-force is reduced: a prediction of the Geometric Clutch Hypothesis is confirmed by micromanipulation experiments. Cell Motility and the Cytoskeleton 44:177-189.
  Lindemann, C.B. and K.S. Kanous (1997) A model for flagellar motility. International Review of Cytology 173:1-72.
  Lindemann, C.B (1996) Functional significance of the outer dense fibers of mammalian sperm examined by computer simulation with the geometric clutch model. Cell Motility and the Cytoskeleton 34:258-270.
  Bird, Z., R. Hard, K.S. Kanous and C.B. Lindemann (1996) Interdoublet sliding in bovine spermatozoa: Its relationship to flagellar motility and the action of inhibitory agents. Journal of Structural Biology 116:418-428.
  Lindemann, C.B. and K.S. Kanous (1995) "Geometric Clutch" hypothesis of axonemal function: key issues and testable predictions. Cell Motility and the Cytoskeleton 31:1-8.
  Lindemann, C.B., J.M. Walker and K.S. Kanous (1995) Ni2+ inhibition induces asymmetry in axonemal functioning and bend initiation of bull sperm. Cell Motility and the Cytoskeleton 30:8-16.
  Lindemann, C.B (1994) A "Geometric Clutch" hypothesis to explain oscillations of the axoneme of cilia and flagella. Journal of Theoretical Biology 168:175-189.
  Lindemann, C.B. (1994) A model of flagellar and ciliary functioning which uses the forces transverse to the axoneme as the regulator of dynein activation. Cell Motility and the Cytoskeleton 29:141-154.
  K.S. Kanous, C. Casey, and Lindemann, C.B. (1993) Inhibition of microtubule sliding by Ni2+ and Cd2+; evidence for a differential response of certain microtubule pairs within the bovine sperm axoneme. Cell Motility and the Cytoskeleton. 26:66-76.
  Lindemann, C.B., A. Orlando and K.S. Kanous (1992) The flagellar beat of rat sperm is organized by the interaction of two functionally distinct populations of dynein bridges with a stable central axonemal partition.Journal of Cell Science Jun;102:249-60.
  Lindemann, C.B., T.K. Gardner, E. Westbrook, K.S. Kanous (1991) The calcium-induced curvature reversal of rat sperm is potentiated by cAMP and inhibited by anti-calmodulin. Cell Motility and the Cytoskeleton 20:316-24.
  Lindemann, C.B., J.S. Goltz, K.S. Kanous, T.K. Gardner, P. Olds-Clarke (1990) Evidence for an increased sensitivity to Ca2+ in the flagella of sperm from tw32/+mice. Molecular Reproduction and Development 26:66-77
  Lindemann C.B. and K.S. Kanous (1989) Regulation of mammalian sperm motility. Archives of Andrology 23:1-22.
  Lindemann, C.B., J.S. Goltz, T.K. Gardner and K.S. Kanous (1988) The interaction of pH and cyclic adenosine 3',5'-monophosphate on activation of motility in Triton X-100 extracted bull sperm. Biological Reproduction 39:1129-36.
  Lindemann, C.B., J.A. O'Brien and F.J. Giblin (1988) An investigation of the effectiveness of certain antioxidants in preserving the motility of reactivated bull sperm models. Biological Reproduction 38:114-20
  Lindemann, C.B. and J.S. Goltz (1988) Calcium regulation of flagellar curvature and swimming pattern in Triton X-100 extracted rat sperm. Cell Motility and the Cytoskeleton 10:420-31
  Lindemann, C.B., J.S. Goltz and K.S. Kanous (1987) Regulation of activation state and flagellar wave form in epididymal rat sperm: evidence for the involvement of both Ca2+ and cAMP. Cell Motility and the Cytoskeleton 8:324-32
  Lindemann, C.B., M. Lipton and R. Shlafer (1983) The interaction of cAMP with modeled bull sperm. Cell Motility and the Cytoskeleton 3:199-210
  Lindemann, C.B., M. Fisher and M. Lipton (1982) A comparative study of the effects of freezing and frozen storage on intact and demembranated bull spermatozoa. Cryobiology 19:20-8
  Lindemann, C.B., I. Fentie and R. Rikmenspoel (1980) A selective effect of Ni2+ on wave initiation in bull sperm flagella. Journal of Cell Biology 87:420-6
  Lindemann, C.B. (1978) A cAMP-induced increase in the motility of demembranated bull sperm models. Cell 13:9-18
  Lindemann, C.B. and I. R. Gibbons (1975) Adenosine triphosphate induced motilty and sliding of filaments in mammalian sperm extracted with Triton X-100. Journal of Cell Biology 65:147-62
  Lindemann, C.B., W.G. Rudd and R. Rikmenspoel (1973) The stiffness of the flagella of impaled bull sperm. Biophysics Journal 13:437-48
  Lindemann, C.B., A.C. Jacklet, S.E. Oriss and R. Rikmenspoel (1973) Control of bull sperm motility. Effects of viscosity, KCN and thiourea. Journal of Mechanochemical Cell Motility 2:7-24
  Lindemann, C.B. and R. Rikmenspoel (1972) Sperm flagellar motion maintained by ADP. Experimental Cell Research 73:255-9
  Lindemann, C.B. and R. Rikmenspoel (1972) Sperm flagella: autonomous oscillations of the contractile system. Science 175:337-8
   
   
  This page was last updated on July 29, 2011
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